M Brothers at Mayo Clinic is a full-service dining experience located in the heart of Jacksonville’s Mayo Clinic, welcoming both visitors and the public. Inspired by the legacy of excellence set forth by The Mayo Brothers, William and Charles Mayo, and continued by the culinary craftsmanship of Matthew and David Medure, M Brothers embodies a passion for quality, innovation, and exceptional hospitality.

With a dedication to high culinary standards, we bring thoughtfully curated dishes, impeccable presentation, and a stylish yet comfortable ambiance to every guest. Whether you're looking for an elegant dinner, a casual lunch, or a relaxing evening in our lounge, M Brothers is the perfect destination for an elevated dining experience.

a medure brothers culinary concept in collaboration with the mayo clinic jacksonville

Welcome to
M Brothers at Mayo 

WELCOME TO M BROTHERS AT MAYO

M Brothers at Mayo Clinic offers a full-service dining experience in the heart of Jacksonville’s Mayo Clinic, welcoming both visitors and the public. Inspired by the Mayo Brothers' legacy and the culinary excellence of Matthew and David Medure, we deliver quality, innovation, and exceptional hospitality.  

With high culinary standards, impeccable presentation, and a stylish yet comfortable ambiance, M Brothers is the perfect spot for an elegant dinner, casual lunch, or a relaxing evening in our lounge.